Working towards a healthier India
PHFI is helping to build institutional and systems capacity in India for strengthening education, training, research and policy development in the area of Public Health.

Adverse Event following Immunization PDF Print

The Adverse Events Following Immunization (AEFI), vaccine safety and quality pillar, aims to support the MoHFW in establishing a functional AEFI surveillance system with a unified database of reports on vaccine safety. The overall goal of AEFI surveillance is to reduce morbidity and mortality due to AEFIs and minimize the negative impact of AEFIs on public health. The specific objectives include:

  • Promptly detect, report and respond to AEFIs
  • Identify unusually high rates of AEFI related to a specific vaccine lot / brand
  • Promptly address programmatic errors through implementation of corrective measures
  • Estimate serious AEFI rates in the population and compare these with local and global data
  • Identify signals of unexpected adverse events and generate new hypotheses about these events that must be confirmed by planned studies and laboratory investigations.

The AEFI pillar at ITSU also hosts the Secretariat for the National AEFI Committee. It provides techno-managerial support to MoHFW for improving surveillance and data support for analysis, follow up and feedback which is essential for policy and program development. The strategic focus of the unit is to

  • Provide techno–managerial support for effective functioning of the National AEFI Committee for design and review of policies and recommendations aimed at strengthening AEFI surveillance;
  • Provide technical assistance to MoHFW and states to strengthen AEFI detection, reporting, investigations, monitoring, causality assessment and response to AEFIs including capacity-building activities and developing standard guidelines;
  • Coordinate AEFI and vaccine safety surveillance activities with other vaccine pharmacovigilance stakeholders including CDSCO (Central Drugs Standards Control Organization), CBHI (Central Bureau of Health Intelligence), PvPI (Pharmacovigilance Programme of India), WHO-ICO NPSP(World Health Organization-India Country Office, National Polio Surveillance Project), UNICEF (United Nations International Children’s Emergency Fund), ICMR, and professional medical and national associations;
  • Liaison with state, national and international agencies for expanding the vaccine safety database and conduct operational and implementation research for further improving AEFI surveillance; and
  • Sustain confidence in immunization as an important public health intervention and develop evidence base for monitoring vaccine safety.
Last Modified : May 11, 2015, 12:22 pm